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Introduction: Whiles in veterinary medicine polymyxins have never ceased to be used for the treatment of Enterobacteria infections, high resistance rates are observed in infections caused by Gram-negative bacteria producing carbapenems against colistin.
Objective: To review the aspects involved in resistance inEscherichia coliencoded by the genemcr-1.
Conclusion: It is believed that this resistance, especially inEscherichia coli, is associated with the intense use of colistin in animal nurture, which represents an important public health problem.
